Scutellaria baicalensis Georgi is the dried root of Scutellaria baicalensis Georgi. It is found in grasslands and dry, highly gravelly slopes;
Characteristics
High purity
Pentoside is a high purity product obtainable through natural extraction and refining production processes, high purity means higher bioavailability.
Safety
Pentoside has been proven to be safe for humans.
Stability
Wogonin has good stability and maintains its activity and efficacy under different environmental and storage conditions.
Applications
Pharmacological Actions
Wogonin is a flavonoid extracted from the root of Scutellaria baicalensis Georgi, family Labiatae, which possesses a variety of pharmacological activities, including antioxidant activity, anti-inflammatory and immunomodulatory effects. In addition, it has neuroprotective effects during cerebral ischaemia.
Anti-cancer effects
The wine precipitate of Scutellaria baicalensis decoction has a significant inhibitory effect on yeast foot swelling in rats, and has anti-inflammatory and anti-allergic effects
Hypolipidemic effect
Scutellaria baicalensis has significant hypolipidemic effects, lowering the levels of serum free fatty acids, triglycerides and liver total cholesterol, free cholesterol and triglycerides in experimental hyperlipidaemic rats, and inhibiting the synthesis of fat from glucose.
Antithrombotic effects
Various components in Scutellaria baicalensis can inhibit platelet aggregation, and its inhibitory effect on platelet aggregation is stronger than that of aspirin. Its mechanism of action is mainly to inhibit thromboxane A2 (TXA2) synthase, so that TXA2 production is reduced; at the same time, it can also increase the level of cAMP, which significantly reduces platelet aggregation; it has the efficacy of anti-thrombosis and prevention of atherosclerosis.
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Diuretic effect
Blood pressure is lowered when urine secretion is increased, with baicalein having the strongest effect. Its diuretic effect may be related to the increase in the levels of PGE1 and PGE2. In the acute diuretic test, baicalein had the strongest effect, followed by baicalein, and poorly by baicalin. It has a diuretic effect.
