Palmitoylethanolamide

Palmitoylethanolamide
Product Name: Palmitoylethanolamide
CAS: 544-31-0
Molecular Formula: C18H37NO2
Molecular weight: 299.49
Content: 99%
Appearance: White crystaline powder

Product Description

Palmitoylethanolamide (PEA), also known as palmitoylethanol, is an endogenous fatty acid amide that belongs to the class of nuclear transcripxion factor agonists. PEA has been shown to bind to a recepxor in the nucleus of cells (nuclear recepxor), affecting a wide range of biological functions associated with chronic pain and inflammation, and is a natural anti-inflammatory agent. The primary target of hexadecanamide is thought to be peroxisome proliferator-activated recepxor alpha (PPAR-α).

Palmitoylethanol is produced naturally by the body and all cells can produce this substance. Its levels are higher when the body is stressed. At the same time, palmitoylethanol is found in a variety of foods, such as egg yolks, peanuts soy lecithin, soya beans, lentils, peas, tomatoes, corn, milk.

Applications

What is Palmitamide Ethanol (PEA)?

Palmitoylethanol is a naturally occurring fatty acid found throughout the body. It may play a role in a variety of biological processes, particularly in the endogenous ceruloplasmin system (ECS).

The body produces more palmitoylethanol in situations where the body and mind are experiencing a combination of stresses. Its production is also induced by infections, pain, allergens, toxins, UV damage, pesticides, gluten and carcinogens. Palmitoylethanol may have properties that alleviate inflammatory reactions and relieve pain, and medical research is being stepped up to determine if it can act positively on a wide range of diseases.

Specifically, it has been demonstrated that palmitoylethanol may have neuroprotective effects and contribute to sympxomatic neurological disorders.

 

How does palmitoylethanol work in the human body?

The mechanism of action of palmitoylethanol is not yet fully understood by scientists. Nevertheless, much progress has been made, thanks to Professor Rita Levi-Montalcini, who elucidated the general mechanism of action of palmitoylethanol in 1992-1996. Since then, she has continued to study the effects of palmitoylethanol on neuropathic pain and allergies.

Palmitoylethanol may provide four major health benefits to humans:

Relief of inflammatory reactions.

Reduces mast cell activation (allergies).

Enhances endogenous pyrogenic system activity.

Initiates specific recepxors in the body

PEA effectively prevents glutamate toxicity in mouse cerebellar granule cells and enhances the motility of microglia. Expression of steroid synthesis-rapidly regulated protein (StAR) and P450scc, including some neurosteroid-forming proteins, was increased in mitochondrial fractions of cells stimulated by PEA.

PEA attenuates the inflammatory response in wild-type mice, is neuroprotective and analgesic, and modulates a number of physiological processes, including nocicepxion, convulsions, and neurotoxicity.

Why choose Sanyi Chemical?

Founded in 2014, Sanyi Chemical has 300 to 350 employees. The company integrates production, sales and service. It focuses on plant extracts, active ingredient monomers, plant powders, natural fruit and vegetable powders, and is dedicated to plant extracts. It is a professional company in R&D and production. Strong technical force, annual output of 500 tonnes, product specifications and stable quality.

Why choose Sanyi Chemical?

Why choose Sanyi Chemical?

Why choose Sanyi Chemical?

Why choose Sanyi Chemical?

Why choose Sanyi Chemical?

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